Month: November 2022

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Sodium is not like the other electrolytes

This thread by Screaming Pectoriloquy is perfect

And a screenshot for when Twitter disappears.

A ten percent reduction in sodium drops it from stone cold normal to rather significant hyponatremia. This is a great example of how precisely sodium is regulated. Sodium regulation is tighter than all other ions. Look at a CMP with calcium, phosphorus, and magnesium added in. (Data is from UCSF).

Range is calculated by taking the difference between high and low and dividing it by the low value. https://www.ucsfhealth.org/medical-tests/phosphorus-blood-test
https://www.ucsfhealth.org/medical-tests/magnesium-blood-test
https://www.ucsfhealth.org/medical-tests/comprehensive-metabolic-panel

Here is a graph of the spread.

Two things immediately should be obvious.

    1. BUN (233%) and creatinine (117%) are not regulated anywhere close to how electrolytes are regulated. Get those guys out of here.
    2. And, the sodium (7%) and chloride (10%) range are nearly identical. Outside of the anion gap, I almost always ignore chloride. 

So let’s simplify this and remove the outliers and shadow.

Look at how tightly sodium is regulated. Regulation of second place, calcium, is THREE times as relaxed.

Every electrolyte is important, but regulating sodium regulates the tonicity in all 42 liters of the internal ocean. Apparently, this is important and sodium is allowed to wander only slightly.

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Download your Twitter Archive. Part 2

The destruction of Twitter seems to continue. Tweet threads like this do not make me optimistic about the future, so download your Twitter experience before Twitter.com is nothing more than a empty website.

After requesting your archive you need to wait for twitter to package up your experience. When they do you will see this on your time line

And this in your email

After I requested my Twitter Archive, it took two days for mine to be available. This is longer than I have seen in the past, makes me think there is a mad rush for the door and a lot of people are doing this.

When you click on the tweet it asks you for your password and then lets you download your Twitter Archive.

It can be a big file. Mine is 5.1 gigs. The archive it is a folder containing two other folders and a text file called Your Archive.html. Launch that and you will be greeted with this.

Clicking on “Tweets” allows you to see your entire history with a nice search function on the right.

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Download your twitter archive right now

I don’t know where Twitter is headed but it doesn’t seem good and I think in the next month or two (weeks?) there is a real possibility of going to twitter.com and seeing a blank page.

#NephTwitter has developed into a wonderful community and if Twitter disappears the community will be forced into a diaspora. NephJC has the podcasts, the newsletter, and the website to communicate our next moves. If you do not subscribe to the newsletter, now would be a good time to do so.

This coming Tuesday, November 15th, NephJC will be discussing EMPA-Kidney and after that discussion ends at 10pm we will be hosting a Twitter Spaces audio chat to discuss about what to do “After Twitter.”

In the mean time, if you have been investing in Twitter for a year, five years, ten years, fourteen years, then you should download your Twitter archive.

To do this go to your profile page and press “More” It will look like this.
Then click on “Settings and Support”

From “Settings and Support” Click on Your Account and then Download an archive of your posts.

Twitter will ask you for your password and then it will e-mail you a note when the archive ready to download.