Non-anion gap Metabolic Acidosis

Non-anion gap metabolic acidosis (PowerpointPDF)
  • Case-based
  • 70 slides, 1 hour
  • Revised May 2013
  • Now optimized for App.GoSoapBox
  • Now available as a screencast.
  • In your chloride intoxication group of causes, add TPN
  • In your GI loss of HCO3, “change HCO3 to HCO3 precursors” since what we lose in diarrhea is not HCO3 per se since pH of the stool is not acidic, we lose citrate, etc which transform into HCO3 eventually
  • Interesting comment on renal bicarb loss: I would add an extra group and call it decrease renal NH4+ excretion and add distal RTA, renal insufficiency and hypoaldosteronism. You don’t lose HCO3 in distal RTA or hypoaldosteronism. You could argue that NH4+ synthesis in proximal tubule generates “new HCO3” but the student will get lost in that concept
  • In the renal HCO3 loss group I would add post-treatment of DKA, and post-hypocapnia
  • Toluene can cause both anion gap and non anion gap metabolic acidosis but the non anion gap is more common because the unmeasured anions are rapidly excreted by the kidneys
  • Pentamidine also blocks ENaC and can cause hyperkalemia

Lecture: Social Media and Health Care

Social Media and Healthcare (Keynote)
  • Huge slide deck that can be mixed and matched for use with different audiences
  • 639 MB for the Keynote file and 62.6 mb for the PDF
  • Find references, links and meta information here.
  • Alternate form of the lecture for a transplant audience (Keynote | PDF)
    • This was an audience of social workers, nurses, transplant recipients, and policy experts.
    • Lecture is cut down to 30 minutes

Clay Shirky on publishing

Saw this on Twitter (thanks Brian):

I retweeted it, but sometimes a retweet is not enough.

 

Publishing is not evolving. Publishing is going away. Because the word “publishing” means a cadre of professionals who are taking on the incredible difficulty and complexity and expense of making something public. That’s not a job anymore. That’s a button. There’s a button that says “publish,” and when you press it, it’s done.

–Clay Shirky

It’s so good I think I will publish it, and by that I mean press a button:

Two more NephTalk Podcasts

I was given the opportunity to work with Satellite Healthcare on their NephTalk podcast and hosted three episodes. The first one, on infection in dialysis units, was posted via RSS and picked up by iTunes. But the next two episodes I hosted were not posted to the RSS feed and so won’t show up in your podcast player of choice (by which I mean Overcast).

So you you’ll have to listen to them like your grand father did, as he walked to school bare foot, through the snow, uphill, both ways, via a web player. Sorry.

Joel Topf, M.D. interviews Steven D. Weisbord, M.D., lead researcher on a study recently published in the New England Journal of Medicine.

Joel Topf, M.D. interviews Linda F. Fried, M.D., lead researcher on a study recently completed for the U.S. Department of Veterans Affairs.