DDAVP Clamp

Bibliography:

Perianayagam, A. et al. (2008) ‘DDAVP is effective in preventing and reversing inadvertent overcorrection of hyponatremia’, Clinical journal of the American Society of Nephrology: CJASN, 3(2), pp. 331–336. https://cjasn.asnjournals.org/content/3/2/331

Gharaibeh, K. A. et al. (2015) ‘Risk factors, complication and measures to prevent or reverse catastrophic sodium overcorrection in chronic hyponatremia’, The American journal of the medical sciences, 349(2), pp. 170–175.

The initial infusion rate (mL/hr) of 3% saline can also be simply calculated as a product of patients’ weight (kg) and desired correction rate (mEq/L/hr)

Sood, L. et al. (2013) ‘Hypertonic saline and desmopressin: a simple strategy for safe correction of severe hyponatremia’, American journal of kidney diseases: the official journal of the National Kidney Foundation, 61(4), pp. 571–578. https://www.ajkd.org/article/S0272-6386(12)01471-0/fulltext

Rafat, C. et al. (2014) ‘Use of desmopressin acetate in severe hyponatremia in the intensive care unit’, Clinical journal of the American Society of Nephrology: CJASN, 9(2), pp. 229–237. https://cjasn.asnjournals.org/content/9/2/229

Adrogué, H. J. and Madias, N. E. (2000) ‘Hyponatremia’, The New England journal of medicine, 342(21), pp. 1581–1589. https://www.nejm.org/doi/pdf/10.1056/NEJM200005253422107

Mohmand, H. K. et al. (2007) ‘Hypertonic saline for hyponatremia: risk of inadvertent overcorrection’, Clinical journal of the American Society of Nephrology: CJASN, 2(6), pp. 1110–1117. https://cjasn.asnjournals.org/content/2/6/1110

Morris, J. H. et al. (2018) ‘Rapidity of Correction of Hyponatremia Due to Syndrome of Inappropriate Secretion of Antidiuretic Hormone Following Tolvaptan’, American journal of kidney diseases: the official journal of the National Kidney Foundation, 71(6), pp. 772–782. https://www.ajkd.org/article/S0272-6386(18)30004-0/fulltext