I had this patient come to me with miserable nephrotic syndrome. Following a biopsy that revealed minimal change disease (MCD), I started her on prednisone and BOOM she got better.
A few months later I tweeted (since deleted, don’t ask) these pics with the caption:
If all I could find a job where all I did was treat minimal change disease all day long, I would sign up in a heart beat.
The point was that MCD is one of the most rewarding diseases nephrologists get to treat. The patients are miserable, you give them the medicine, and they get better. Yes, I know there is a terrifying relapse rate, and high dose steroids are no walking the park, but compared to the disease we typically treat in nephrology, this one is particularly rewarding.