Slide Shows

I have been thinking about the role of social media in the pandemic. This is the first medical crisis not the age of the public physician and social media. It has resulted in some some fascinating developments. Some of the changes that came about because of the pandemic will indelibly change ...

Here is the video: Here is the Keynote: Toluene explained ...

We tweet and think the tweet evaporates after a day or two (actually, that’s particularly optimistic, most disappear after an hour or two) but occasionally a reply can come from the distant past like a message from a deep space probe. Today, someone replied to a tweet I wrote in May of 2019. ...

Here is the lecture in PDF and Keynote format. ...

Everyone talks about the importance of mentors in career development, but there is another type of Fairy God Mother that doesn’t get as much press but can be just as important, this is the Sponsor. A sponsor doesn’t give advice and guide you like a mentor does, but when opportunities ...

Earlier this year I got the opportunity to speak at Brigham and Women’s Nephrology division. I had spent a lot of time and thought in updating my Social Media and Medical Education talk. For the first time I added Podcasts and Tweetorials, two of the most exciting developments in social ...

This is one of my favorite lectures. It starts with Izzy getting fired on Grey’s Anatomy to the metabolic consequences of crack cocaine in dialysis patients to the imaginary monogenic diseases of Ethan Hawke and Denzel Washington. Metabolic alkalosis is a topic that is rarely taught at all. ...

This is a formal lecture on the Tweetorial I posted about a patient with beer drinkers potomania but presented with increased serum osmolality due to ethanol intoxication. Keynote • PowerPoint • PDF Note: The presentations are designed to be displayed in KeyNote, the powerpoint version may be ...

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I have had the honor to teach the M2s since the medical school opened it’s doors. Here are the blog posts I have written to answer medical students questions or to post the latest materials (Handouts, Keynotes). ...

Last year’s NephJC on Jen Titze’s study on simulated Mars missions and sodium handling really baked my noodle. Titze’s arm of research breaks the foundational laws of body fluids. Partly to help myself grasp the information, and partly to help spread this paradigm shifting ...

Last fall, Dr. Davis (@IDPharmProf) asked if I would be interested in speaking about antibiotic induced AKI. She was thinking of submitting an idea for a session on kidney disease and antibiotics. Later, she told me I would be sharing the stage with Bruce Mueller (@BAMPharmD), who would be talking ...

This is the topic that I was asked to speak about at the International Society of Peritoneal Dialysis meeting in Vancouver. I have never had to speak specifically about the negative aspects of social media in medicine, though I have addressed in previous lectures. I thought it was a good exercise. ...

David Goldfarb (@weddellite) and I put on a fluid, electrolyte and acid-base variety show at KidneyCON. The itinerary: IV fluid taste test Hypernatremia Management of calcium phosphate stones: to K-Citrate or not? Management of chronic hyponatremia, use of DDAVP Aspirin toxicity Hyperkalemia Both ...

I started this calcium series in January. This was the second lecture. The fellows are clever so instead of a formal lecture the presentation is designed to stimulate discussion and pose a number questions using real cases. Keynote  |  PDF ...

This is my Water and Osmoles lecture edited for students, specifically pre-clinical M2s. Keynote | Powerpoint I then broke this down into two PowerPoint presentations Volume Regulation   and Sodium Regulation   ...

This is my sodium and dysnatremia lecture edited for residents. It is long and will take two hours to deliver. Keynote | PDF ...

Metabolic Alkalosis (PDF, Keynote) New lecture Feb 2012 50 minutes the flow of the lecture around chloride deficiency is a bit choppy Updated March 2013 ...

Initiation of dialysis (Keynote, PowerPoint) Completely revised January 2012 A little short 40 minutes Needs data on poor function of nursing home patients initiated on dialysis and data on increased mortality Mondays and Tuesdays. Fellow level ...

Water, diuretics ands dysnatremia (PDF, Powerpoint) 89 slides Probably 80-90 minutes for a full delivery The Dysnatremia section is largely identical to the Sodium lecture above Fuller description of the lecture at this post Updated July 2011 ...

Anemia and CKD: The Epo Saga (Keynote, PDF) 82 slides Delivered in about 45 minutes New in June 2011 Revised October 2011 Added data on future agents: Hematide and HIF-stabilizers ...

Free water clearance (Powerpoint, PDF) 17 slides a little tired updated 5/26/11 ...

A lecture on giving lectures (Keynote) The keynote file is 130mb, so be patient ...

Cardiorenal syndrome (Keynote, PDF) Needs a bit on the various loop diuretics Needs the data showing harm from diuretics with ADHF Updated 4/18/11 82 slides, 1:22 minutes ...

Hemodialysis for the Internist. An Update. (Keynote, PDF) ...

Hemodialysis School: Dialysis Dose (Powerpoint, PDF) Updated October 2011 86 slides, 1 hour Covers NCDS, HEMO, FHN, spKt/V, eKt/V, stdK/t/V ...

Fractional Excretion of Sodium (Powerpoint is no longer available. The file got corrupted and I can’t open it. | PDF ) ...

HIV and the Kidney (Keynote, PDF)   Updated April 2013 The lecture was about one hour. The section on APOL1 is rough. I would like a slide describing the transgenic mouse model studies by Klotman that showed that transcription of nef and pol are central to the disease. I need some notes ...

Uric Acid, Gout and Hypertension (Keynote, PDF) For awhile I was really fascinated with this subject. Here are the posts I wrote on the topic. Updated June 2011 Added CKD data included the two RCTs of allopurinol on CKD progression (both positive) 121 slides Keynote is 96mb, PDF 59mb You can do ...

Geriatric CKD (Keynote, PDF) ...

Sodium including electrolyte free water (Keynote, Powerpoint PDF) This is an older version of my hyponatremia lecture. This lecture has gone through various versions and though I like my most current version, others may like older variations better. Additionally the Keynote version (2014) is ...

Acute renal failure from the basics to the latest advances (Keynote 71 MB) ...

Acid-Base (Powerpoint) This is a lecture written for medical students getting their first exposure to acid-base physiology. This is a version for residents where the learners have previous experience with acid base. (Powerpoint | PDF) Scope: primary disorder second primary disorders affecting ...

Case of a drunk with hypokalemia, hypomagnesemia, refeeding syndrome and beer drinkers potomania. (Keynote, PDF) ...

Imaging in Acute Renal Failure. My talk at 2010 ASN Renal Week (Powerpoint, PDF) ...

Diabetic Nephropathy with a focus on proteinuria as a poor prognostic indicator (Keynote, PDF) updated and tightened up October 2012 Includes Bardoxolone implosion ...

Diabetic Nephropathy (Powerpoint, PDF) ...

Non-anion gap metabolic acidosis (Powerpoint, PDF) Case-based 70 slides, 1 hour Revised May 2013 Now optimized for App.GoSoapBox Now available as a screencast. In your chloride intoxication group of causes, add TPN In your GI loss of HCO3, “change HCO3 to HCO3 precursors” since what we ...

Hyponatremia (Keynote, PDF) 91 slides, 1 hour Revised Feb 2013 ...

Social Media and Healthcare (Keynote) Huge slide deck that can be mixed and matched for use with different audiences 639 MB for the Keynote file and 62.6 mb for the PDF Find references, links and meta information here. Alternate form of the lecture for a transplant audience (Keynote | PDF) This ...

Journey to NephMadness (Keynote | PDF) 45 minutes Screencast of the lecture is available here. ...

Here is my Renal Grand Rounds from Duke that I gave this October. Here is a copy of the most recent version of the deck (Keynote, 912MB) from the University of Michigan talk I gave last week. ...

This morning I gave a lecture on how to do a presentation to the residents at St John Hospital and Medical Center. Here is the presentation: How to give a Lecture (375 MB) I used some material from this older version Meta lecture (148 MB) Much of the lecture was just stepping through the SGLT2i ...

At Lankenau Medical Center in Philadelphia at 8:00 AM, January 12. I will be talking about Spooky Sodium 👻. Here is the title slide If you can’t make it, first of all, what’s wrong with you? But second of all don’t worry, you can get the high points from the man who discovered ...

One hour lecture on NAGMA. Just some small changes edits from the last time I gave it. It is one of the few lectures that is still in PowerPoint. It is due for a complete overhaul. It also needs a slide on the treatment of RTA that covers the amount of bicarbonate in a 650 … Continue ...

This past autumn I was invited to give a lecture at the Michigan ACP. I love that meeting. I decided to talk about the mortality data on SGLT2 inhibitors and how we got that data and how curious that data is. Then, last week I had the opportunity to give the lecture again for grand … ...

This is a new fellow level lecture, i.e. very motivated but shallow knowledge. It could be adapted for residents. This one is due for an upgrade. Note that a lot of the slides are hidden. As is, it is over an hour. Keynote           ...

My practice has a number of nurse practitioners and physician assistants. The partners do quarterly teaching sessions for them. It is some of my favorite teaching. They come to each session with a lot of experience and the sessions are more like guided conversations rather than traditional. ...

I was invited to speak at the Wayne State Alumni Day. It felt pretty special to come back to my old medical school and speak. They put together a great morning of lectures for their CME session. Here is a Twitter moment from the morning WSU School of Medicine Alumni Day I gave my herbal … ...

I am attending on the dialysis service in December and the residents requested a lecture on hypertension. This was a sharp group so I decided to do an update on the literature and go through four papers in the session. It went well. We had lots of great discussions and answered a lot questions. ...

Diabetic kidney disease Diabetic kidney disease from Joel Topf Hyperkalemia Hyperkalemia, an update from Joel Topf The survey on the treatment of mild hyperkalemia: How would you manage the hyperkalemia https://t.co/11ekJFdGkh — (((Joel Topf, MD))) (@kidney_boy) June 5, 2016 Results of the: ...

This lecture is treatment and practical focused lecture. Intended audience is nephrology nurse practitioners. Based on the AUA stone guidelines (PDF), which are excellent. Kidney Stones – Created with Haiku Deck, presentation software that inspiresLink to an Excel Spreadsheet of Oxalate ...

Just a tutorial on ABG interpretation Powerpoint PDF ...

A pharmacist from Blue Cross, Kim Moon, sent me an e-mail and told me she was a fan of the PBFluids and my and twitter. That, of course, instantly made her my newest bestie. She then asked me to do a webinar addressing common issues that prevent primary care doctors from prescribing ACEi/ARB to ...

I love it when fellows turn the tables on their attendings and school them on how the kids do it today. Kamran Boka is currently a critical care fellow at Henry Ford Hospital but when he was a wee resident he worked with me at St John Hospital. This is an excellent lecture, make sure … ...

Sodium, sodium and less sodium Keynote | PDF ...

Here is the potassium lecture in all its glory. Keynote (332.4 MB) PDF (131.8 MB) If you want to know more about why I allow people to download an editable version of the lecture read this. The videos are here: Part One: Introduction 28 minutes Part Two: Hypokalemia 22 minutes ...

I can’t post to Vimeo until next week. So google docs this time. Part 2 Part one is here ...

Once agin I have the honor of teaching the second year medical students at Oakland University William Beaumont School of Medicine. I have 4 points of contact with the students: I get to run the first TBL of the renal section. It is on sodium and water I get to run an Acid-Base workshop I … ...

Powerpoint and PDF Supplemental questions (PDF) Link is now fixed. Sorry. ...

Gave this lecture yesterday. Needs some tweaking, it is a little long on ecg changes with hyperkalemia and the calcium section is light. I will add other electrolytes. Keynote (141mb)PDF (61mb) ...

In August of 2013, I went to Chicago for the ASN Board Review Class. The week long class was filled with great lectures and compelling teachers, but it was a review and I had solid knowledge of most sessions, but one session was different. Warren Kupin (Hey, Warren, we are still waiting for ...

A few years ago I was talking one of my mentors at Kidney Week, John Asplin. He mentioned that he taught an integrated lecture on metabolic alkalosis and hypokalemia. I thought this was an inspired idea. Teaching separate classes on both subjects results in a lot of overlap because the renal ...

I was supposed to give a lecture to the St John Residents. Stayed up late working on an ARF lecture, showed up and…I was the only one there. Turns out they had an inservice exam today. All those late nights for nothing. Well here are the slides: Keynote (43 mb)PDF (25 mb) Acute Kidney& ...

I gave the intro to Acid-Base Lecture to the SJHMC residents this morning. As promised here are the practice problems: Practice Q and A PDFPractice Q and A Pages File And the presentation: Presentation PDFPresentation Powerpoint File ...

This is my NAGMA lecture. It contains a thorough, but not exhaustive, overview of renal tubular acidosis. Any feedback would be appreciated. NAGMA from joel topf on Vimeo. I need a better technology to make these. Still way too tedious. ...

I have been trying to use GoSoapBox to add some interactivity to my lectures. My first attempt did not work out at all like I wanted it. I used quizzes instead of polls. Then I added  GoSoapBox elements to my non-anion gap lecture and I tried to use it at McClaren Macomb a couple of … ...

I gave a lecture on HIV renal disease to the ID section yesterday. I give this lecture every couple of years. I swear that lecture changes more from year to year than any subject I talk about. The lecture was about one hour.  The section on APOL1 is rough. I would like a slide describing ...

On Tuesday December 4, I will be presenting grand rounds for St John Hospital and Medical Center. This page has the references, lecture notes and a copy of the slides. PDF of the slide deck (17.3 MB) Social Media in Health Care from Joel Topf One of the gimmicks of the talk was that a … ...

For the past few years I have had the honor of giving the July 1st morning lecture for the internal medicine residents at St John Hospital and Medical Center. Unfortunately, July 1st was a Sunday and Monday mornings are dedicated to a formal sign out rounds in our division. So July 3rd was my ...

My family took a vacation to Chicago and a friend asked if I could give an acid-base lecture. So I dropped  in as an electrolyte sharpshooter and delivered my non-anion gap metabolic acidosis lecture. The revised lecture is in the usual place. ...

Just gave the metabolic alkalosis lecture. Turned out pretty good. The lecture was about 50 minutes. Keynote | PDF Updated: Now with less errors. ...

This is a fellow level lecture. I built it off an old lecture from 2003 or 2004. It is remarkable how much data has emerged since then. Of coarse the IDEAL Trial has put a dagger in the heart of early initiation but the observational data in agreement with abandoning early initiation has also ...

I reworked an old lecture from ’05 on urea kinetics. The old lecture had a hideous purple background, so changing that to black would have been enough but I added a number of cool touches to fully update it. It worked pretty well, though the end’s pacing is off. PowerPoint | PDF I ...

As has been the tradition since 2008, I had the honor of giving the morning report on July 1st for the St John Hospital and Medical Center Internal Medicine Residency Program. July one, openning day of the academic year. The conference room was crackling with the energy of fresh interns and ...

Today I did a noon conference on sodium for the neph fellows. Instead of a comprehensive sodium lecture I focused on a number of different elements and interesting aspects of hyponatremia. Mostly a deeper dive into aspects that you don’t have time to cover in standard sodium. ...

I gave the cardiology fellows at St John Hospital and Medical Center a lecture on cardiorenal syndrome this morning. I revised and expanded the lecture I used for the residents: I added my rant regarding the Ronco’s codification of cardiorenal syndrome I added the latest NEJM article on ...

This post really resonates with me: The Ten Commandments of PowerPoint and I wish that I had included it in my lectuer from last week on how to give a lecture. The chief resident at St John Hospital and Medical Center asked me to do morning report on giving better presentations. It was an ...

On the first Friday of every month I give a lecture to the residents at St. John Hospital and Medical Center. I like to do an electrolyte lecture but for March the chief resident asked me to talk about cardiorenal syndrome. In researching the lecture I came across this article by Claudio Ronco. ...

The title for the talk was dialysis for the internist and I focused on recent advances in the field of hemodialysis including: Plavix for fistula maturation. Doesn’t work. Aggrenox for graft preservation. Does work. HeRO grafts for patients with central venous stenosis Poor outcomes for ...

In 2006 I had to give the fellows a lecture on nocturnal dialysis. I remember being delighted with how it turned out. It was a fellow-level lecture that would have little appeal to non-nephrologists. The lecture goes into the different ways to measure dialysis dose and deep-dives into the ...

AKI Lecture 2010 View more presentations from Joel Topf. This is a significant upgrade from the version I posted a couple of years ago. I put the lecture together right before the ATN trial was published. I finally got around to updating the presentation to include that data. I also updated the ...

I have been doing a monthly fluid and electrolyte conference for the residents at St. John. Today we did a case of hypernatremia initially due to hypercalcemia and then due to nephrogenic diabetes insipidus. Hypernatremia Hypercalcemia Case Vignette View more presentations from Joel Topf. ...

For the last 6 weeks I have been pounding the computer finishing and perfecting my lecture which I gave at Grand Rounds at both Providence Hospital and St John’s Hospital. I delivered the second one yesterday. Here is the lecture with an audio track. My presentations are not self-contained ...

I was scheduled to give a talk on disorders of sodium and water to the fellows yesterday. We have a particularly clever cohort of fellows this year and I really couldn’t give them a warmed over version of my resident and student sodium lecture so I put together this talk which looks five ...

It was incredible. The residents, who usually sleep through the second half of noon conference, were completely charged up and by the end of the lecture were holding up lighters and chanting my name. I dove from the stage and was passed around like a Rock God. Here is the lecture in powerpoint ...

Our fellowship director asked me to do a lecture on osmolar gap. At first I thought that this was an odd topic as toxic alcohols, the standard reason for determining an osmolar gap are relatively rare findings and I was worried I’d be able to find enough to talk about for an hour. I’m ...

I did my standard Acid-Base work shop with the medical students and Providence Hospital last week. Here is the handout. Corrected an embarrassing error on page 9 and changed a few of the problems a little bit. Acid-Base handout.pdf And the pages document if you want to modify it: Acid-Base pages ...

Lecture on IV Fluids and sodium I had eight 3rd year medical students. I did a quick pole and 6 of the 8 had or were planning on getting an iPhone/iPod touch. One student had an Android G1. No Blackberries, no Windows Mobile. Is it too early to declare a winner in the medical smart … ...

On July first I gave a lecture on IV fluids, total body water and hyponatremia. This handout is similar to the lecture I give to the medical students titled sodium and water. It adds a half baked section on potassium but this handout really needs to have th sodium section tightened up and, ...

I gave my third board review class for the graduating residents at Providence. They requested RTAs. Here are the supporting materials: Power point presentation (link) Active ABG problem generator (link) Good luck. ...

As the Nephrology Fellow Network recently covered the etiology of cardiovascular disease in dialyzors is unique from the general public. Use of statins, the foundation of preventative cardiology, has repeatedly failed to prevent cardiovascular vascular disease (CVD) among dialyzors. One reason for ...

Today I did a lecture for the fellows on hyperkalemia. It is interesting that nearly none of the content I use to teach the residents and students is used in a lecture for the fellows. Same subject complete rewrite. I plan on doing four posts on hyperkalemia from this lecture: EKG changes Dialysis ...

Third in the series of interesting fluid and electrolyte cases. I would add a slide on where I was going in potassium before the anorexia section. SlideSpace botches the torn paper frames I used through out the lecture so if you have Keynote, download and look at the native file. Here is a link& ...

I gave a lecture to the third-year medical students at Providence hospital on Friday. I thought the lecture went well but on saturday I was going over an admit note by one of the students in the class. The patient was admitted with DKA but had a combined metabolic acidosis and respiratory. ...

I am trying to do a monthly lecture for the Providence internal medicine residents on electrolytes. I gave my second one last Friday. It was an interesting case we had of hypernatremia on the consult service last summer. I did this lecture in Keynote and I am blown away by how good it presents ...

I did a lecture at Providence last week. I was scheduled to just give a electrolyte lecture without any further guidance. I pulled out two interesting cases I had seen in the last few weeks. Both patients have a non-anion gap metabolic acidosis, but one is hypokalemic and the other is. ...

Yesterday I gave a great lecture on interpreting ABG results. I added a problems set for gap-gap analysis and added a section on the osmolar gap. I also improved the anion gap section with my new favorite nemonic. Forget PLUMSEEDS, forget MUDSLEEPS, forget MUDPILES. The new hotness is GOLD MARK: G ...

Yesterday I lectured the St John ER residency program. The ER residency has an impressive commitment to education. They set aside a half day every wednesday for their resident to get dedicated didactic time. They have great attendance with a good number of attendings showing up. I have been asked ...

Today I gave my second lecture of the year for the St John Residency. I used my Acid-Base workshop handout and added a slide show to facilitate the large group. I still called on individual residents to answer questions to keep them involved. I started the lecture with some audience participation. ...

Today I gave the first lecture of the ’08-’09 Academic Year. This was morning report for internal medicine. I did a lecture on IVF, diuretics, total body water and dysnatremia. It was a good lecture but Powerpoint only. I am about half-way done with the killer handout I am working on ...