Hello Dr. Topf,
I hope you are enjoying your weekend. I had a question in regards to one of your lectures. I was wondering why there is a low level of Uris acid in euvolemic hyponatremia but not in hypervolemic or hypovolemic hyponatremia. Also, how is it that Na taken in equals Na excreted in euvolemic hyponatremia?
All the best,
- Decreased uric acid clearance with decreased renal perfusion
- Increased uric acid clearance with increased perfusion of the kidney
This is similar to what we see with urea. The following description of urea handling gives a model that will work for uric acid, though the truth of uric handling is much more complex.