In February I’m giving grand rounds on the Potassium Wars (what, you didn’t realize we are in the opening stages of the potassium wars?). I was looking at the original research on Kayexalate from 1961 and came across this ad. Check out the doses of spironolactone they were slinging:
Why we needed Kayexalate in the first place
400 mg of spironolactone, daily and this is in a world without loop diuretics!