In August, the NEJM pushed out three articles examining the role of sodium in human disease. These are the subject of September 9’s #NephJC.
The first article is the Association of Urinary Sodium and Potassium Excretion with Blood Pressure. This question used the large epidemiologic study, Prospective Urban Rural Epidemiology (PURE) to answer the question.
PURE enrolled 157,543 adults age 35 to 70 from 18 low-, middle-, and high-income countries on 5 continents.
The mean sodium excretion was 4.9g and the mean potassium excretion was 2.1 grams.
|It was difficult for me to understand the difference between the Observed excretion and Usual excretion but the authors seemed to reference the Usual excretion as the definitive curve.|